The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2025

Filed:

Jun. 25, 2021
Applicant:

Syntara Limited, Frenchs Forest, AU;

Inventors:

Alan Duncan Robertson, Warawee, AU;

Alison Dorothy Findlay, Frenchs Forest, AU;

Alberto Buson, Macquarie Park, AU;

Craig Ivan Turner, Frenchs Forest, AU;

Dieter Wolfgang Hamprecht, Frenchs Forest, AU;

Jonathan Stuart Foot, Frenchs Forest, AU;

Mandar Deodhar, Frenchs Forest, AU;

Wolfgang Jarolimek, Frenchs Forest, AU;

Serena Becchi, Wollstonecraft, AU;

Bernard Walter Balleine, Paddington, AU;

Marcella Canton, Padua, IT;

Libero Vitiello, Padua, IT;

Bert Blaauw, Padua, IT;

Assignee:

Syntara Limited, Frenchs Forest, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 255/54 (2006.01); A61P 9/00 (2006.01); A61P 21/00 (2006.01);
U.S. Cl.
CPC ...
C07C 255/54 (2013.01); A61P 9/00 (2018.01); A61P 21/00 (2018.01);
Abstract

The present invention relates to novel compounds which are capable of inhibiting semicarbazide-sensitive amine oxidase (SSAO/VAP-1) and monoamine oxidase B (MAO-B). These compounds are useful for treatment of a variety of neuromuscular diseases, such as muscular dystrophies, and neuroinflammatory diseases, including both peripheral and central disorders in human subjects, as well as in pets and livestock. In addition, the present invention relates to pharmaceutical compositions containing these compounds, as well as various uses thereof.


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