The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2025

Filed:

Oct. 15, 2020
Applicant:

University of Cincinnati, Cincinnati, OH (US);

Inventors:

Leyla Esfandiari, Cincinnati, OH (US);

Gregory Harris, Cold Spring, KY (US);

Assignee:

University of Cincinnati, Cincinnati, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/50 (2006.01); A61N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3633 (2013.01); A61L 27/3878 (2013.01); A61L 27/50 (2013.01); A61N 7/00 (2013.01); A61L 2400/12 (2013.01); A61L 2430/32 (2013.01); A61N 2007/0026 (2013.01);
Abstract

Provided herein are implantable biomaterials for promoting regeneration of an injured biological tissue, the biomaterials including piezoelectric materials and an extracellular matrix specific to the injured biological tissue, wherein the piezoelectric materials and the extracellular matrix are electrospun together to provide tissue-specific bioactive piezoelectric nanofiber scaffolds. Also provided herein are methods of fabricating a tissue-specific bioactive piezoelectric nanofiber scaffold and methods of promoting regeneration of injured biological tissue by implanting the disclosed bioactive piezoelectric scaffolds.


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