The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Mar. 31, 2017
Applicant:
University of Cincinnati, Cincinnati, OH (US);
Inventors:
Assignees:
University of Cincinnati, Cincinnati, OH (US);
Molecular Targeting Technologies, Inc., West Chester, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61K 51/12 (2006.01); C07B 59/00 (2006.01); C07D 209/14 (2006.01); C07D 403/06 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0446 (2013.01); A61K 51/1234 (2013.01); C07B 59/002 (2013.01); C07D 209/14 (2013.01); C07D 403/06 (2013.01); C07B 2200/05 (2013.01);
Abstract
Compositions that include a phenol group conjugated to a lipid group to form a phenolic lipid. The lipid group may include a fluorophore and at least one lipid anchor. The lipid anchor may have a carbon number that ranges between 7 carbon atoms and 22 carbon atoms. Also, included are methods of making and using such phenolic lipids. Further included are methods of iodinating hydrophobic compounds such as phenolic lipids in aqueous based iodination protocols. Cosolvent formulations for use in such methods are also described.