The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Jan. 30, 2023
Ionizing irradiation sterilization of bacterial minicell-based biopharmaceuticals and methods of use
Applicant:
Vaxiion Therapeutics, Llc, San Diego, CA (US);
Inventors:
Matthew J. Giacalone, San Diego, CA (US);
Gary H. Ward, San Diego, CA (US);
Assignee:
VAXIION THERAPEUTICS, LLC, San Diego, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/74 (2015.01); A61K 9/00 (2006.01); A61K 47/26 (2006.01); A61L 2/00 (2006.01); C07K 14/24 (2006.01); C07K 14/33 (2006.01);
U.S. Cl.
CPC ...
A61K 35/74 (2013.01); A61K 9/0019 (2013.01); A61K 47/26 (2013.01); A61L 2/0035 (2013.01); C07K 14/24 (2013.01); C07K 14/33 (2013.01); A61L 2202/21 (2013.01); Y02A 50/30 (2018.01);
Abstract
Disclosed herein are methods of terminally sterilizing bacterial minicells or compositions comprising bacterial minicells by exposure to ionizing irradiation. Also disclosed are terminally sterilized bacterial minicells, pharmaceutical compositions comprising the bacterial minicells, and methods of using the bacterial minicells and pharmaceutical compositions.