The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Feb. 26, 2021
Applicant:
Sanofi, Paris, FR;
Inventors:
Monsif Bouaboula, Belmont, MA (US);
Zhuyan Guo, Belmont, MA (US);
Stéphane Poirier, Stoneham, MA (US);
Maysoun Shomali, Belmont, MA (US);
Fangxian Sun, Melrose, MA (US);
Assignee:
Sanofi, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61K 31/40 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 31/40 (2013.01); A61P 35/00 (2018.01);
Abstract
Herein are provided a combination of alpelisib and of 6-(2,4-dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing such a combination, and the therapeutic uses thereof, in particular for the treatment of cancer, including breast cancer.