The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2025

Filed:

Mar. 09, 2022
Applicant:

Rutgers, the State University of New Jersey, New Brunswick, NJ (US);

Inventors:

Nilgun E. Tumer, Belle Mead, NJ (US);

Xiao-Ping Li, Flemington, NJ (US);

Jacques Roberge, Piscataway, NJ (US);

David Augeri, Princeton, NJ (US);

Bin Cao, New Brunswick, NJ (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/34 (2006.01); A61K 31/381 (2006.01); A61K 31/40 (2006.01); A61K 31/41 (2006.01); A61K 31/426 (2006.01); A61K 31/69 (2006.01); A61K 45/06 (2006.01); A61P 39/02 (2006.01); C07D 207/337 (2006.01); C07D 277/56 (2006.01); C07D 307/54 (2006.01); C07D 333/24 (2006.01); C07D 333/34 (2006.01); C07D 333/38 (2006.01); C07D 333/40 (2006.01); C07D 333/70 (2006.01); C07D 409/04 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/381 (2013.01); A61K 31/34 (2013.01); A61K 31/40 (2013.01); A61K 31/41 (2013.01); A61K 31/426 (2013.01); A61K 31/69 (2013.01); A61K 45/06 (2013.01); A61P 39/02 (2018.01); C07D 207/337 (2013.01); C07D 277/56 (2013.01); C07D 307/54 (2013.01); C07D 333/24 (2013.01); C07D 333/34 (2013.01); C07D 333/38 (2013.01); C07D 333/40 (2013.01); C07D 333/70 (2013.01); C07D 409/04 (2013.01); C07F 5/025 (2013.01);
Abstract

The disclosure provides in one aspect a method of treating, ameliorating, and/or preventing toxicity caused by a ribosome inactivating protein (RIP) in a subject. In certain embodiments, the method comprises administering to the subject a therapeutically effective amount of at least one compound of the disclosure.


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