The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Feb. 25, 2025
Applicant:
Maxymune Therapeutics, Inc., Los Altos, CA (US);
Inventors:
Bernd Jandeleit, Menlo Park, CA (US);
Guangyao Gao, Los Altos, CA (US);
Wolf-Nicolas Fischer, Sunnyvale, CA (US);
Gordon Ringold, Los Altos Hills, CA (US);
Assignee:
Maxymune Therapeutics, Inc., Los Altos, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07C 311/33 (2006.01); A61K 31/10 (2006.01); A61K 31/145 (2006.01); C07C 311/39 (2006.01); C07C 311/43 (2006.01); C07C 311/44 (2006.01); C07C 317/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/145 (2013.01); A61K 31/10 (2013.01); C07C 311/33 (2013.01); C07C 311/39 (2013.01); C07C 311/43 (2013.01); C07C 311/44 (2013.01); C07C 317/14 (2013.01); C07C 2601/14 (2017.05); C07C 2601/16 (2017.05); C07C 2602/10 (2017.05);
Abstract
Phenylalanine-based inhibitors of the Large Amino Acid Transporter 1 (LAT1) are disclosed. The compounds are useful in modulating the transcellular transport of substrates of LAT1 such as large neutral amino acids. The compounds are useful in immunomodulation therapies.