The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2025

Filed:

Oct. 25, 2021
Applicant:

Avedro, Inc., Waltham, MA (US);

Inventors:

Marc D. Friedman, Needham, MA (US);

Pavel Kamaev, Lexington, MA (US);

Mikhail Smirnov, North Andover, MA (US);

Assignee:

Avedro, Inc., Waltham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 9/007 (2006.01); A61F 9/008 (2006.01);
U.S. Cl.
CPC ...
A61F 9/0079 (2013.01); A61F 9/007 (2013.01); A61F 9/008 (2013.01); A61F 9/00825 (2013.01); A61F 2009/00851 (2013.01); A61F 2009/00872 (2013.01); A61F 2009/00893 (2013.01);
Abstract

A system for corneal treatment includes a light source that activates cross-linking in at least one selected region of a cornea treated with a cross-linking agent. The light source delivers photoactivating light to the at least one selected region of the cornea according to a set of parameters. The system includes a controller that receives input relating to the cross-linking agent and the set of parameters. The controller includes computer-readable storage media storing: (A) program instructions for determining cross-linking resulting from reactions involving ROS including at least peroxides, superoxides, and hydroxyl radicals, and (B) program instructions for determining cross-linking from reactions not involving oxygen. The controller executes the program instructions to output a calculated amount of cross-linking in the at least one selected region of the cornea. In response to the calculated amount of cross-linking, the light source adjusts at least one value in the set of parameters.


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