The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2025

Filed:

Sep. 23, 2021
Applicants:

Everest Medical Innovation Gmbh, Zug, CH;

Regents of the University of Minnesota, Minneapolis, MN (US);

Inventors:

Franz Schmidlin, Geneva, CH;

John Bischof, St. Paul, MN (US);

Paul A. Iaizzo, White Bear Lake, MN (US);

Qi Shao, Plymouth, MN (US);

Pegah Ranjbartehrani, Falcon Heights, MN (US);

David A. Ramirez, St. Paul, MN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 18/02 (2006.01); A01N 1/125 (2025.01); A01N 1/128 (2025.01); A61B 18/00 (2006.01);
U.S. Cl.
CPC ...
A01N 1/125 (2025.01); A01N 1/128 (2025.01); A61B 18/02 (2013.01); A61B 2018/00547 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/0088 (2013.01); A61B 2018/0293 (2013.01);
Abstract

A cryoprotective composition configured to be applied during cryotreatment of a patient includes at least one biodegradable and/or bioerodible fluid agent and at least one non-toxic cryoprotectant agent. A therapeutically effective amount of the cryoprotective composition deposited in a body space of the patient in proximity to the cryotreatment remains within at least a portion of the body space for a duration of the cryotreatment. At least a portion of a body tissue proximate to the body space is viable after the cryotreatment. A method of protecting a surgical site during prostate cryosurgery is also provided. The method includes injecting a therapeutically effective amount of the cryoprotective composition into the body space, wherein the body space is a periprostatic space of a patient.


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