System and methods for adaptive bandwidth-efficient encoding of genomic data

Abstract

A system and methods for adaptive bandwidth-efficient data encoding comprising: a sequence analyzer configured to analyze a received sequence dataset, maintain a count of unique characters, and identify positions where the unique character count increases by a power of two; an adaptive sourceblock optimizer that determines and dynamically adjusts optimal sourceblock sizes based on dataset characteristics; and a data deconstruction engine that deconstructs the dataset into sourceblocks and creates codewords for storage or transmission. The system analyzes sequence complexity, alphabet size, and character frequency distribution to optimize sourceblock sizes, and uses machine learning to improve decision-making over time. This adaptive approach enhances compression efficiency across varied genomic data types, including genome graphs, while maintaining data integrity and security. The system efficiently encodes, stores, and transmits complex genomic and bioinformatic datasets, addressing the growing challenges in data storage and bandwidth limitations.