The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Dec. 28, 2021
Quiver Holdings Inc., Cambridge, MA (US);
Christopher Werley, Cambridge, MA (US);
Yang Lu, Cambridge, MA (US);
Arvind Mohan, Cambridge, MA (US);
Pin Liu, Cambridge, MA (US);
Graham T. Dempsey, Cambridge, MA (US);
Nate Bremmer, Cambridge, MA (US);
William Amar, Cambridge, MA (US);
Hongkang Zhang, Wellesley, MA (US);
QUIVER HOLDINGS INC., Cambridge, MA (US);
Abstract
The inventions provide microscopes for imaging samples within wells of multi-well plates. Microscopes of the disclosure include a beam homogenizer system that shapes a beam from a light source into a shape specific to the bottom of a well of a multi-well plate. In particular, microscopes of the disclosure can illuminate wells for imaging by passing light through a prism that is beneath the sample. The light enters the prism from the side and as refracted into the well at a steep angle such that the light only illuminates about a bottom ten microns of the well. The beam homogenizer shapes the light from the light source so that, instead of hitting the prism as a spot with an irregular shape, the light enters the prism in a substantially rectangular pattern with homogeneous optical power level over the pattern.