The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Jun. 28, 2019
Fred Hutchinson Cancer Center, Seattle, WA (US);
University of Washington, Seattle, WA (US);
Jesse Bloom, Seattle, WA (US);
Adam S. Dingens, Seattle, WA (US);
Katharine H. D. Crawford, Seattle, WA (US);
Caelan Radford, Seattle, WA (US);
Fred Hutchinson Cancer Center, Seattle, WA (US);
University of Washington, Seattle, WA (US);
Abstract
Cell-stored barcoded viral protein deep mutational scanning libraries are described. The libraries can be used to map resistance mutations to therapeutic treatments. The libraries can be used to predict viruses that become resistant to therapeutic compounds and/or may more easily evolve to infect new species. The libraries can also be used to more safely study dangerous viruses that normally require high safety biocontainment facilities. The libraries include features that allow efficient collection and assessment of informative data, obviating many bottlenecks of previous approaches.