The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2025

Filed:

Apr. 08, 2022
Applicant:

The University of Hong Kong, Hong Kong, CN;

Inventors:

Hein Min Tun, Hong Kong, CN;

Sai Sai Zhang, Hong Kong, CN;

Hau Tak Chau, Hong Kong, CN;

Fung Yu Huang, Hong Kong, CN;

Man Fung Yuen, Hong Kong, CN;

Wai Kay Seto, Hong Kong, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); A61K 35/741 (2015.01); A61K 35/747 (2015.01); A61P 1/16 (2006.01); C12Q 1/6883 (2018.01); C12Q 1/689 (2018.01); A61K 35/00 (2006.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/689 (2013.01); A61K 35/741 (2013.01); A61K 35/747 (2013.01); A61P 1/16 (2018.01); C12Q 1/6883 (2013.01); A61K 2035/115 (2013.01); C12Q 1/686 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Disclosed are microbial biomarkers and methods for accurate non-invasive diagnosis of non-alcoholic fatty liver disease (NAFLD) in subjects. The microbial biomarkers includeas well as its strains and subspecies. The microbial biomarkers includesp. 5-2. The methods include measuring abundance or copy number of the one or more microbial biomarkers in a sample from the subject. The sample may be bodily fluid, mucus, or stool. Also described are methods of treating a subject with NAFLD by administering to the subject a composition containingand/orsp. 5-2.


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