The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2025

Filed:

Aug. 01, 2017
Applicant:

California Institute of Technology, Pasadena, CA (US);

Inventors:

Long Cai, Pasadena, CA (US);

Chee Huat Eng, Pasadena, CA (US);

Sheel Shah, Pasadena, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6841 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6841 (2013.01); C12Q 2525/161 (2013.01); C12Q 2537/143 (2013.01); C12Q 2537/149 (2013.01); C12Q 2563/107 (2013.01); C12Q 2563/179 (2013.01); C12Q 2565/102 (2013.01); C12Q 2565/514 (2013.01); C12Q 2565/518 (2013.01);
Abstract

The present invention, among other things, provides technologies for detecting and/or quantifying nucleic acids in cells, tissues, organs, or organisms. Pre-designed barcodes are associated with specific molecular targets through sequential hybridization experiments. A pseudo-color based barcoding scheme is described that overcomes the limitations in the previous generation of the technology. The current method can be applied to both in vitro and in situ analysis.


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