The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Jul. 08, 2019
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Michael Christopher Jewett, Evanston, IL (US);
Anne E. D'aquino, Evanston, IL (US);
Assignee:
Northwestern University, Evanston, IL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01); C12N 1/20 (2006.01); C12N 9/10 (2006.01); C12N 15/10 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); C12N 1/20 (2013.01); C12N 9/104 (2013.01); C12N 15/1058 (2013.01); C12N 15/113 (2013.01); C12Y 203/02012 (2013.01); C12N 2310/128 (2013.01);
Abstract
Disclosed are engineered or modifiedribosomes and methods, components, compositions, and kits for preparing and identifying engineered or modifiedribosomes. The engineered or modifiedribosomes may be prepared and identified under a set of defined conditions, such as in the presences of a engineered or modified tRNA comprising a non-natural, non-α-amino acid monomer (NNA), in order to obtain an engineered or modified ribosome that utilizes the engineered or modified tRNA as a substrate for synthesizing a polymer comprising the NNA.