The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2025

Filed:

Jan. 07, 2020
Applicant:

Pivot Bio, Inc., Berkeley, CA (US);

Inventors:

Douglas Higgins, Berkeley, CA (US);

Andrew Abel Prior, Oakland, CA (US);

Assignee:

Pivot Bio, Inc., Berkeley, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/74 (2006.01);
U.S. Cl.
CPC ...
C12N 15/74 (2013.01);
Abstract

The present disclosure is drawn to methods of utilizing nucleic acid barcodes and corresponding amplifying sites in cells in which the barcodes naturally occur. These barcodes and amplifying sites are reconfigured into a single nucleic acid cassette that provides for ease of use in tagging particular species, strains, or variants of cells, each with a different barcode. These barcodes can be used to track the colonization capabilities of the barcoded cells. The present disclosure further provides for assays that utilize natural barcodes to measure relative microbial colonization ability of a plant root system.


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