The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2025

Filed:

Dec. 22, 2021
Applicant:

Entos Pharmaceuticals Inc., Edmonton, CA;

Inventors:

John Lewis, Edmonton, CA;

Konstantin Stoletov, Edmonton, CA;

Lian Willetts, Edmonton, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/00 (2006.01); A61K 31/7088 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01); A61K 33/00 (2006.01); A61P 35/04 (2006.01); C07K 16/28 (2006.01); C07K 16/44 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/00 (2013.01); A61K 31/7088 (2013.01); A61K 31/7105 (2013.01); A61K 31/713 (2013.01); A61K 33/00 (2013.01); A61P 35/04 (2018.01); C07K 16/28 (2013.01); C07K 16/44 (2013.01); G01N 33/574 (2013.01); G01N 2800/56 (2013.01);
Abstract

Disclosed are methods of diagnosing and treating metastatic cancer in a subject. The methods involve detecting or modulating the expression of at least one of Kif3b, ACTB, SRPK1, TM EM 229b, C14orf142, KB-1460A1.5, ACTC1, Nr2f1, KIAA0922, KDELR3, APBA2, miRNA 130b, miRNA 374b, or miRNA 122 in a biological sample from the subject.


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