The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Nov. 30, 2018
Applicants:
Stemrim Inc., Osaka, JP;
Osaka University, Osaka, JP;
Inventors:
Katsuto Tamai, Suita, JP;
Takashi Shimbo, Suita, JP;
Eiji Sasaki, Suita, JP;
Takehiko Yamazaki, Toyonaka, JP;
Assignees:
STEMRIM INC., Osaka, JP;
OSAKA UNIVERSITY, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0775 (2010.01); A61K 35/28 (2015.01); C07K 14/47 (2006.01); G01N 33/50 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0663 (2013.01); A61K 35/28 (2013.01); C07K 14/47 (2013.01); G01N 33/5073 (2013.01); A61K 38/00 (2013.01);
Abstract
The inventors discovered that ectodermal mesenchymal stem cells circulating in peripheral blood that are induced by necrotic tissue damage contribute to the regeneration of damaged tissue. On the basis of this discovery, provided are ectodermal mesenchymal stem cells, a method for producing the same, and a screening method for a substance having pluripotent stem cell inductive activity, the screening method using cells induced by necrotic tissue damage in peripheral blood as an index.