The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
May. 24, 2020
The Regents of the University of Michigan, Ann Arbor, MI (US);
Stel Technologies, Llc, Ann Arbor, MI (US);
Lisa M. Larkin, Ann Arbor, MI (US);
Ellen M. Arruda, Ann Arbor, MI (US);
Michael J. Smietana, Memphis, TN (US);
Pablo Moncado-Larrotiz, San Francisco, CA (US);
Haley Titinger, Ann Arbor, MI (US);
The Regents of the University of Michigan, Ann Arbor, MI (US);
STEL TECHNOLOGIES, LLC, Ann Arbor, MI (US);
Abstract
A bioreactor capable of producing complex, three-dimensional tissue constructs has improved media transfer and increased controllability with regard to exposure to the external environment. The bioreactor includes an external surface, a first tissue culture side for culturing a first cell source in a first tissue culture support region, a second tissue culture side for culturing a second cell source in a second tissue culture support region, and a plurality of ports. At least one of the ports of the plurality of ports extend from the first tissue culture support region of the first tissue culture side to the external surface. The plurality of ports can include an external port that is configured to be a liquid inlet when the bioreactor is in a first orientation and a gas outlet when the bioreactor is in a second orientation.