The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Dec. 04, 2020
Korea Atomic Energy Research Institute, Daejeon, KR;
In Gyu Kim, Daejeon, KR;
Rae Kwon Kim, Sejong, KR;
Jai Ha Lee, Daejeon, KR;
Chang Kyu Heo, Daejeon, KR;
Yeon Jee Kahm, Hwaseong-si, KR;
Byung Chul Shin, Seoul, KR;
Eun Wie Cho, Daejeon, KR;
Chun Jeih Ryu, Seoul, KR;
Min Kyu Kim, Seoul, KR;
Mun Ju Choi, Seoul, KR;
KOREA ATOMIC ENERGY RESEARCH INSTITUTE, Daejeon, KR;
Abstract
The present invention relates to novel antibodies or antigen-binding fragments thereof that specifically bind to TransMembrane 4 Superfamily Member 4 (TM4SF4). These antibodies or antigen-binding fragments thereof exhibit proliferation inhibitory activity of cancer cells so as to effectively prevent or treat cancer, and reduce the self-renewal ability of cancer stem cells to be usefully used even in the treatments of cancer with a poor prognosis in conventional anticancer treatments.