The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Jul. 17, 2020
Applicant:
Legend Biotech Ireland Limited, Dublin, IE;
Inventors:
Tao Zhao, Nanjing, CN;
Yuanyuan Peng, Nanjing, CN;
An Tang, Nanjing, CN;
Sujuan Wang, Nanjing, CN;
Shuai Yang, Nanjing, CN;
Wang Zhang, Nanjing, CN;
Shu Wu, Nanjing, CN;
Ruidong Hao, Shanghai, CN;
Assignee:
Legend Biotech Ireland Limited, Dublin, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 40/31 (2025.01); A61K 39/395 (2006.01); A61K 40/11 (2025.01); A61K 40/42 (2025.01); A61P 35/00 (2006.01); C07K 14/705 (2006.01); C07K 14/71 (2006.01); C07K 14/725 (2006.01); C07K 16/18 (2006.01); C12N 5/0783 (2010.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70521 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4202 (2025.01); A61K 40/4229 (2025.01); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70596 (2013.01); C07K 14/71 (2013.01); C07K 16/18 (2013.01); C12N 5/0636 (2013.01); C12N 5/0638 (2013.01); C12N 5/0646 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); A61K 2239/31 (2023.05); A61K 2239/38 (2023.05); C07K 2317/22 (2013.01); C07K 2317/569 (2013.01); C07K 2317/622 (2013.01);
Abstract
Provided herein are anti-DLL3 chimeric antigen receptors (CARs), DLL3 binding proteins and uses of such CARs or DLL3 binding proteins in the treatment of DLL3 associated disorders, such as small cell lung cancer.