The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Sep. 20, 2024
Applicant:
Quanta Therapeutics, Inc., South San Francisco, CA (US);
Inventors:
Hong Lin, Exton, PA (US);
Juan Luengo, Phoenixville, PA (US);
Audrey Hospital, North Wales, PA (US);
Jin Zeng, Audubon, PA (US);
Pei Gan, Claymont, DE (US);
Assignee:
QUANTA THERAPEUTICS, INC., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61K 31/551 (2006.01); A61K 31/553 (2006.01); A61K 31/554 (2006.01); A61K 31/675 (2006.01); C07D 487/04 (2006.01); C07D 487/08 (2006.01); C07D 495/10 (2006.01); C07D 495/20 (2006.01); C07F 9/6561 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61K 31/55 (2013.01); A61K 31/551 (2013.01); A61K 31/553 (2013.01); A61K 31/554 (2013.01); A61K 31/675 (2013.01); C07D 487/04 (2013.01); C07D 487/08 (2013.01); C07D 495/10 (2013.01); C07D 495/20 (2013.01); C07F 9/6561 (2013.01);
Abstract
Provided herein are KRAS modulating compounds, such as compounds of Formula (I), (I-A), (I-B), (I-C), (I-C*), (I-D), (I-E), (I-F), (I-G), (I-H), (I-I), (I-J), or pharmaceutically acceptable salts, solvates, stereoisomers, atom labelled, or tautomers of any one thereof. The compounds provided herein are useful for modulating KRAS G12D and/or other G12 mutants.