The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2025

Filed:

Apr. 24, 2024
Applicant:

Mirati Therapeutics, Inc., San Diego, CA (US);

Inventors:

Xiaolun Wang, San Diego, CA (US);

Anthony Ivetac, San Diego, CA (US);

Svitlana Kulyk, San Diego, CA (US);

John David Lawson, Carlsbad, CA (US);

Matthew Arnold Marx, San Diego, CA (US);

Christopher Ronald Smith, San Diego, CA (US);

Assignee:

Mirati Therapeutics, Inc., Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01); C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61P 35/00 (2018.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to compounds that inhibit at least one of KRas wild type, KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor.


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