The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Jan. 27, 2025
Applicant:
Nimbus Wadjet, Inc., Boston, MA (US);
Inventors:
Derun Li, Boston, MA (US);
Angela V. West, Franklin, MA (US);
Justin Caravella, Cambridge, MA (US);
Nathan E. Genung, Boston, MA (US);
Florian Bartels, Berlin, DE;
Robert Lee Dow, Groton, CT (US);
Silvana Marcel Leit De Moradei, Burlington, MA (US);
Nikolay Sitnikov, Berlin, DE;
Assignee:
Nimbus Wadjet, Inc., Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/4985 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 31/551 (2006.01); C07D 471/14 (2006.01); C07D 491/147 (2006.01); C07D 495/14 (2006.01); C07D 513/14 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4985 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61K 31/551 (2013.01); C07D 471/14 (2013.01); C07D 491/147 (2013.01); C07D 495/14 (2013.01); C07D 513/14 (2013.01); C07D 519/00 (2013.01);
Abstract
The present disclosure is directed to compounds of Formula I: and pharmaceutically acceptable salts thereof, and compositions thereof, as well as methods of treatment of cancers such as those involving WRN protein.