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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12421210 B1

PDFFull Text
Date of Patent:
Sep. 23, 2025

Filed:

Oct. 05, 2019

Fused bicyclic heterocycles as therapeutic agents

Applicant:

New York University, New York, NY (US);

Inventors:

John K. Dickson, Apex, NC (US);

Andrew S. Chi, New York, NY (US);

Xinyan Huang, Paramus, NJ (US);

Nadim Shohdy, Garden City, NY (US);

Assignee:

NEW YORK UNIVERSITY, New York, NY (US);

Attorney:

McDonnell Boehnen Hulbert & Berghoff LLP

Primary Examiner:

Jeffrey H Murray

Assistant Examiner:

Kevin S Martin

Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 209/94 (2006.01); C07D 333/54 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 405/14 (2006.01); C07D 409/12 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 491/048 (2006.01); C07D 491/052 (2006.01); C07D 495/04 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01); C07D 513/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 209/94 (2013.01); C07D 401/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/048 (2013.01); C07D 491/052 (2013.01); C07D 495/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01); C07D 513/14 (2013.01);
Abstract

This disclosure relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to nicotinamide phosphoribosyltransferase (NAM FT) expression. More particularly, this disclosure relates to fused bicyclic heterocyclic compounds and pharmaceutical compositions thereof, methods of inhibiting NAM FT with these compounds, and methods of treating diseases related to NAMPT expression.

Find Patent Forward Citations

Dickson, John. (2025). Fused bicyclic heterocycles as therapeutic agents (U.S. Patent No. 12421210). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12421210

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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