Aryl-n-aryl derivatives for treating a rna virus infection

Abstract

A compound of formula (Ie): wherein Yrepresents an aryl group, Xrepresents a —O— group, a —NH— group, a —S— group, a —CO—NH— group, a —NH—CO—NH— group, a —NH—CO— group, a —CH(OH)— group, a —CH(COOH)NH— group, a —CH(COOCH)NH— group, a —C(OH)(CHOH)—, a group, a divalent 5-membered heteroaromatic ring comprising 1, 2, 3 or heteroatoms, a —SO— group, or a —SO—NH— group, Yrepresents a hydrogen atom, a hydroxyl group, a (C-C)alkoxy group, a —CHC(OH), a COOR, wherein Rrepresents a hydrogen atom or a (C-C)alkyl group, a morpholinyl group, a dihydropyranyl group, a group, a group, a —PO(OR)(OR') group, wherein Rand R′independently represents a hydrogen atom or a (C-C)alkyl group, an oxetanyl group, a —Si(CH)group, a —NHCOO—(C-C)alkyl group, or a —CRRRgroup, or any of its pharmaceutically acceptable salt and pharmaceutical compositions containing them and to synthesis process for manufacturing them.