The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Nov. 18, 2020
Lupin Limited, Mumbai, IN;
Rajender Kumar Kamboj, Pune, IN;
Shaji George Kochumalayil, Bangalore, IN;
Spinvin Venugopal, Kochi, IN;
Kamlesh Jyotindra Padiya, Pune, IN;
Prabakaran Kamalakannan, Pune, IN;
Kumar Ram Naik, Pune, IN;
Sachin Subhash Ingawale, Pune, IN;
Bhavani Shankar Rajesh, Pune, IN;
Rajendra Ganpati Powar, Pune, IN;
LUPIN LIMITED, Mumbai, IN;
Abstract
A process for manufacturing substituted chroman compounds in an economically scalable manner, without the use of pyrophoric reagents. Also disclosed herein are chroman compound synthesis routes that do not include column chromatography purification steps. The disclosure also relates to the intermediates used in the synthesis. In particular, the disclosure relates to the synthesis of the Calcium sensing receptor (CaSR) modulating agent 2-methyl-5-((2R,4S)-2-((((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoic acid, its intermediates and pharmaceutically acceptable salts thereof.