The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Jan. 08, 2021
Applicant:
Cedars-sinai Medical Center, Los Angeles, CA (US);
Inventors:
Michael Freeman, West Hollywood, CA (US);
Mirja Rotinen, Beverly Hills, CA (US);
Ramachandran Murali, Beverly Hills, CA (US);
Sungyong You, Los Angeles, CA (US);
Assignee:
CEDARS-SINAI MEDICAL CENTER, Los Angeles, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 237/08 (2006.01); A61K 31/165 (2006.01); A61K 31/397 (2006.01); A61K 31/40 (2006.01); A61K 31/416 (2006.01); A61K 31/4164 (2006.01); A61K 31/417 (2006.01); A61K 31/445 (2006.01); A61K 31/45 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07C 233/31 (2006.01); C07C 237/22 (2006.01); C07C 259/06 (2006.01); C07D 205/04 (2006.01); C07D 207/09 (2006.01); C07D 207/16 (2006.01); C07D 211/60 (2006.01); C07D 211/76 (2006.01); C07D 211/78 (2006.01); C07D 231/56 (2006.01); C07D 233/64 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C07C 237/08 (2013.01); A61K 31/165 (2013.01); A61K 31/397 (2013.01); A61K 31/40 (2013.01); A61K 31/416 (2013.01); A61K 31/4164 (2013.01); A61K 31/417 (2013.01); A61K 31/445 (2013.01); A61K 31/45 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07C 233/31 (2013.01); C07C 237/22 (2013.01); C07C 259/06 (2013.01); C07D 205/04 (2013.01); C07D 207/09 (2013.01); C07D 207/16 (2013.01); C07D 211/60 (2013.01); C07D 211/76 (2013.01); C07D 211/78 (2013.01); C07D 231/56 (2013.01); C07D 233/64 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6886 (2013.01); C07B 2200/07 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01);
Abstract
Provided herein are compositions and methods for treating, inhibiting and/or reducing the severity of cancer in subjects in need thereof. The methods include providing an agent that inhibits expression or activity of ONECUT2 and administering a therapeutically effective amount of the agent so as to treat, inhibit and/or reduce the severity of cancer in the subject.