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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12420258 B1

PDFFull Text
Date of Patent:
Sep. 23, 2025

Filed:

Jan. 23, 2024

Diatomaceous earth composition with a low endotoxin content

Applicant:

Sartorius Stedim Biotech Gmbh, Göttingen, DE;

Inventors:

Karl Pflanz, Gleichen, DE;

Florian Hebenstreit, Beberstedt, DE;

Andreas Pickl, Klein Schneed, DE;

Assignee:

Sartorious Stedim Biotech GmbH, Gottingen, DE;

Attorneys:

Sandberg Phoenix & von Gontard, PC

Steven T. Kazmierski

Primary Examiner:

Yong L Chu

Int. Cl.
CPC ...
B01J 20/14 (2006.01); A61L 2/08 (2006.01); B01D 37/02 (2006.01); B01J 20/28 (2006.01); B01J 20/30 (2006.01); B65B 55/02 (2006.01); B65D 65/40 (2006.01); C12M 1/00 (2006.01);
U.S. Cl.
CPC ...
B01J 20/14 (2013.01); A61L 2/081 (2013.01); B01D 37/02 (2013.01); B01J 20/28004 (2013.01); B01J 20/28016 (2013.01); B01J 20/2805 (2013.01); B01J 20/3028 (2013.01); B65B 55/02 (2013.01); B65D 65/40 (2013.01); C12M 47/02 (2013.01); C12M 47/10 (2013.01); A61L 2202/21 (2013.01);
Abstract

The present invention relates to a diatomaceous earth composition with a low endotoxin content, comprising an agglomerated mixture of calcined diatomaceous earth particles and water, wherein the mass ratio of calcined diatomaceous earth particles and water is in the range of 1:1.0 to 1:2.0, and wherein the endotoxin content of the diatomaceous earth composition is equal to or less than 0.5 EU/mL. In a further aspect, the present invention relates to a method for producing the diatomaceous earth composition with a low endotoxin content. In another aspect, the present invention relates to the use of the diatomaceous earth composition with a low endotoxin content as a precoat agent for the precoat filtration in biopharmaceutical applications.

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