The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Oct. 11, 2019
Applicants:
Academisch Ziekenhuis Leiden (H.o.d.n. Lumc), ZA Leiden, NL;
Technische Universität München, Munich, DE;
Scintomics Gmbh, Fürstenfeldbruck, DE;
Inventors:
Fijs W. B. Van Leeuwen, ZA Leiden, NL;
Hans-Jurgen Wester, Munich, DE;
Tessa Buckle, ZA Leiden, NL;
Danny Van Willigen, ZA Leiden, NL;
Margret Schottelius, Munich, DE;
Saskia Kropf, Fürstenfeldbruck, DE;
Assignees:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/10 (2006.01); A61K 49/00 (2006.01); A61K 51/04 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
A61K 49/106 (2013.01); A61K 49/0002 (2013.01); A61K 51/0482 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01);
Abstract
This invention relates to compounds of formula I or Ia: (I) (Ia). Y is EuK, —EuAF, —EuPG, -L-EuE; Z is a chelating moiety; and the other substituents are as defined herein. Also provided are formulations comprising such a compound, as well as methods of imaging or methods for the treatment of cancer comprising use of such a compound or formulation.