The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Dec. 26, 2019
Institut National DE Recherche Pour L'agriculture, L'alimentation ET L'environnement, Paris, FR;
Centre National DE LA Recherche Scientifique, Paris, FR;
Sorbonne Universite, Paris, FR;
Assistance Publique-hôpitaux DE Paris, Paris, FR;
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Institut Du Cerveau ET DE LA Moelle Epiniere, Paris, FR;
Pierre Fafournoux, Auriers, FR;
Jacques Mallet, Paris, FR;
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION L'ENVIRONNEMENT, Paris, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
SORBONNE UNIVERSITE, Paris, FR;
ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS, Paris, FR;
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), Paris, FR;
INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE, Paris, FR;
Abstract
A nucleic acid for the controlled expression of a nucleic acid encoding a pro-apoptotic protein in an individual, including: a regulatory polynucleotide including a minimal promoter and at least one AARE (amino acid response element) nucleic acid, the regulatory polynucleotide being activated in an individual upon consumption of a diet deficient in at least one essential amino acid; and a nucleic acid encoding a pro-apoptotic protein, which is placed under the control of the regulatory polynucleotide.