The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Apr. 13, 2022
Applicant:
Cnpharm Co., Ltd., Seoul, KR;
Inventors:
Hojun Kim, Seoul, KR;
Geun-Woo Jin, Seoul, KR;
Assignee:
CNPharm Co., Ltd., Seoul, KR;
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); C07D 407/12 (2006.01);
U.S. Cl.
CPC ...
A61K 47/545 (2017.08); C07D 407/12 (2013.01);
Abstract
Synthesizing a docetaxel-aconitic anhydride conjugate using docetaxel, including: mixing aconitic anhydride with a chlorinating reagent to produce a first mixture; dissolving the first mixture in an organic solvent to produce a dissolved mixture; stirring the dissolved mixture; evaporating the organic solvent from the dissolved mixture to produce a second mixture; washing the second mixture with an impurity remover to remove impurities and to produce an aconitic anhydride chloride solution; and mixing the docetaxel with the produced aconitic anhydride chloride solution to produce the docetaxel-aconitic anhydride conjugate.