The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2025

Filed:

Mar. 15, 2024
Applicant:

Astellas Institute for Regenerative Medicine, Westborough, MA (US);

Inventors:

Roger Gay, Acton, MA (US);

Judson Ratliff, Harvard, MA (US);

Romma E. Southwick, Waban, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/26 (2006.01); A61K 9/08 (2006.01); A61K 31/7004 (2006.01); A61K 31/728 (2006.01); A61K 33/06 (2006.01); A61K 33/14 (2006.01); A61K 35/28 (2015.01); A61K 35/30 (2015.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01); A61K 47/36 (2006.01); A61P 27/02 (2006.01);
U.S. Cl.
CPC ...
A61K 47/26 (2013.01); A61K 9/08 (2013.01); A61K 31/7004 (2013.01); A61K 31/728 (2013.01); A61K 33/06 (2013.01); A61K 33/14 (2013.01); A61K 35/28 (2013.01); A61K 35/30 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/36 (2013.01); A61P 27/02 (2018.01);
Abstract

Some aspects of this disclosure provide clinical media that support viability, re-plating efficiency, and repopulation capacity of cells and tissues during storage for up to 48 hours or longer. The clinical media provided herein are also useful for clinical irrigation. Cell or tissue preparations comprising a cell population or tissue and a clinical medium as provided herein are also provided, as are methods for generating such preparations. Methods for using the clinical media and cell and tissue preparations provided herein, for example, for administering an effective amount of cells or tissue to a subject in need thereof, are also disclosed.


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