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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12419944 B1

PDFFull Text
Date of Patent:
Sep. 23, 2025

Filed:

Oct. 18, 2022

Dnabii vaccines and antibodies with enhanced activity

Applicant:

Research Institute AT Nationwide Children's Hospital, Columbus, OH (US);

Inventors:

Lauren O. Bakaletz, Hilliard, OH (US);

Steven D. Goodman, Hilliard, OH (US);

Assignee:

Research Institute at Nationwide Children's Hospital, Columbus, OH (US);

Attorney:

Foley & Lardner LLP

Primary Examiner:

Mary Maille Lyons

Int. Cl.
CPC ...
A61K 39/102 (2006.01); A01N 63/50 (2020.01); A61K 45/06 (2006.01); A61P 31/04 (2006.01); C07K 14/285 (2006.01); C07K 16/12 (2006.01); G01N 33/569 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/102 (2013.01); A01N 63/50 (2020.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); C07K 14/285 (2013.01); C07K 16/1242 (2013.01); G01N 33/56911 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/20 (2013.01); C07K 2317/24 (2013.01); C07K 2317/55 (2013.01); C07K 2319/00 (2013.01); G01N 2333/285 (2013.01);
Abstract

The disclosure provides methods and compositions that are useful to lessen and/or cure bacterial biofilms and treat diseases or disorders associated with biofilms using one or more novel polypeptide vaccines, antibodies, antibody fragments and compositions. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics.

Find Patent Forward Citations

Bakaletz, Lauren. (2025). Dnabii vaccines and antibodies with enhanced activity (U.S. Patent No. 12419944). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12419944

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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