The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Oct. 08, 2023
Applicant:
Embrient, Inc., San Diego, CA (US);
Inventor:
Barry E. Rothenberg, Del Mar, CA (US);
Assignee:
Embrient Inc., San Diego, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/728 (2006.01); A61K 35/19 (2015.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/728 (2013.01); A61K 35/19 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01);
Abstract
A method of treatment is presented for alleviating and/or repairing damage associated with M1 macrophage-driven inflammation through administration of high molecular weight hyaluronic acid (HMW-HA), optionally in combination with platelet-rich plasma (PRP) and/or anti-Stabilin-2 antibodies. Preferred embodiments are formulated for parenteral administration and either directly or indirectly suppress M1 macrophage activity, and/or directly indirectly promote M2 macrophage polarization.