The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Sep. 20, 2024
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Cystetic Medicines, Inc., San Carlos, CA (US);
Martin D. Burke, Champaign, IL (US);
Agnieszka Lewandowska, Savoy, IL (US);
Corinne Soutar, Urbana, IL (US);
Jeffry G. Weers, Half Moon Bay, CA (US);
Thomas Tarara, Burlingame, CA (US);
Danforth P. Miller, San Carlos, CA (US);
The Board of Trustees of the University of Illinois, Urbana, IL (US);
cystetic Medicines, Inc., San Carlos, CA (US);
Abstract
Disclosed are pharmaceutical compositions, comprising: (i) amphotericin B or a pharmaceutically acceptable salt or hydrate thereof; (ii) cholesterol; (iii) phospholipids, comprising hydrogenated soy phosphatidylcholine and distearoylphosphatidylglycerol; and (iv) calcium chloride (CaCl)). Also disclosed are methods of using the pharmaceutical compositions for treating a disease or disorder (e.g., cystic fibrosis), increasing the pH of airway surface liquid, increasing bicarbonate secretion into airway surface liquid, and increasing a subject's forced expiratory volume in one second.