The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2025

Filed:

Feb. 14, 2025
Applicants:

Chongqing Pharmaceutical Research Institute Co., Ltd., Chongqing, CN;

Yaopharma Co., Ltd., Chongqing, CN;

Inventors:

Wei Nie, Chongqing, CN;

Xiaolong Kerri Yan, Chongqing, CN;

Haoying Xu, Chongqing, CN;

Qiang Liu, Chongqing, CN;

Zhichao Xu, Chongqing, CN;

Hongkun Qin, Chongqing, CN;

Xiang Li, Chongqing, CN;

Hongyi Liu, Chongqing, CN;

Yaming Cao, Chongqing, CN;

Xiaoqing Bai, Chongqing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/10 (2006.01); A61K 31/437 (2006.01); A61K 31/438 (2006.01);
U.S. Cl.
CPC ...
A61K 31/437 (2013.01); C07D 471/10 (2013.01);
Abstract

The present disclosure relates to a GLP-1R agonist compound and use thereof, and specifically provides a compound represented by Formula I, or an isotope-labelled compound, a stereoisomer, or a pharmaceutically acceptable salt thereof, and use thereof as a medicament. The compound exhibits excellent agonistic effects and pharmacodynamic properties on GLP-1R and, as a modulator, is useful for manufacturing a medicament for the treatment, amelioration, or prevention of metabolic diseases and related diseases, thus having broad application prospects.


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