The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Oct. 24, 2022
Consejo Superior DE Investigaciones Cientificas (Csic), Madrid, ES;
Bioinicia, S.l., Valencia, ES;
Jose Maria Lagaron Cabello, Valencia, ES;
Cristina Prieto Lopez, Lugo, ES;
Jose Manuel Valle Baz, Castellon de la Plana, ES;
David Galan Nevado, Malaga, ES;
Julia Hrakovsky, Gdynia, PL;
Consejo Superior de Investigaciones Cientificas (CSIC), Madrid, ES;
BIOINICIA, S.L., Valencia, ES;
Abstract
The present invention relates to a pharmaceutical formulation comprising at least one active pharmaceutical ingredient (API) having low aqueous solubility or a pharmaceutically acceptable salt thereof in the form of particles of a size between 1 and 800 nm, wherein said particles are encapsulated within a large microparticle of a size between 1 and 100 μm formed by a matrix comprising at least an excipient. Therefore, the API is entrapped or encapsulated in the microparticles of excipients. This pharmaceutical formulation contains the pharmaceutical active ingredient having improved solubility and subsequently supra-bioavailability.