The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2025

Filed:

Feb. 10, 2020
Applicant:

Lubrizol Advanced Materials, Inc., Cleveland, OH (US);

Inventors:
Assignee:

Lubrizol Advanced Materials, Inc., Cleveland, OH (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 8/64 (2006.01); A61Q 19/06 (2006.01); A61Q 19/08 (2006.01); C07K 5/113 (2006.01); C07K 7/06 (2006.01);
U.S. Cl.
CPC ...
A61K 8/64 (2013.01); A61Q 19/06 (2013.01); A61Q 19/08 (2013.01); C07K 5/1021 (2013.01); C07K 7/06 (2013.01); A61K 38/00 (2013.01);
Abstract

A compound of formula (I) R-W-X-AA-AA-AA-AA-AA-AA-Y-Z-R, a stereoisomer and/or cosmetically acceptable salt thereof, and a method of treatment using the compound are described. In the compound, AAis Asp, Gly, Asn, Gln, Ala or no amino acid; AAis Val, Ile, Leu or Ala; AAis Tyr, Phe, Trp, Lys, Arg or His; AAis Lys, Arg, His, Pro or Val; AAis Asn, Asp, Gln or no amino acid; AAis Thr, Ala, Ser or no amino acid. The compounds are useful for the treatment of the symptoms of skin aging and, in particular, for the treatment of skin wrinkles, the treatment of a sagging appearance of the skin, and/or the reduction of facial asymmetry.


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