The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 23, 2025

Filed:

Jul. 12, 2023
Applicant:

Ventana Medical Systems, Inc., Tucson, AZ (US);

Inventors:

Fernando Jose Rebelo Do Couto, Pleasanton, CA (US);

Zhiming Liao, Livermore, CA (US);

Andrea Muranyi, Tucson, AZ (US);

Kandavel Shanmugam, Oro Valley, AZ (US);

Shalini Singh, Tucson, AZ (US);

Yifei Zhu, San Jose, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/22 (2006.01); C07K 16/30 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57496 (2013.01); C07K 16/22 (2013.01); C07K 16/30 (2013.01); C07K 2317/20 (2013.01); C07K 2317/34 (2013.01); C07K 2317/92 (2013.01); G01N 2333/485 (2013.01);
Abstract

The invention provides anti-human pro-epiregulin and anti-human amphiregulin antibodies and methods of using the same. Anti-EREG antibodies raised against amino acids 148-169 and 156-169 of the human EREG protein, and anti-AREG antibodies raised against amino acids 238-252 of the human AREG protein are disclosed. Methods of using these antibodies to detect EREG and AREG and kits and other products for performing such methods are also disclosed.


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