The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2025

Filed:

Oct. 21, 2021
Applicant:

Consejo Superior DE Investigaciones Cientificas (Csic), Madrid, ES;

Inventors:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/0205 (2024.01); G01B 11/04 (2006.01); G01N 15/02 (2024.01); G01N 15/10 (2024.01); G01N 15/14 (2024.01); G01N 15/1429 (2024.01); G01N 15/1434 (2024.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
G01N 15/0211 (2013.01); G01B 11/04 (2013.01); G01N 15/1429 (2013.01); G01N 15/1434 (2013.01); G01N 33/487 (2013.01); G01N 15/02 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1027 (2024.01); G01N 2015/1029 (2024.01); G01N 15/14 (2013.01);
Abstract

The method uses a suspended resonating microcapillary device, and obtains simultaneously three parameters of the analytes: mass, size and refractive index, enabling the unequivocal classification of the analytes flowing in real time, based on the resonance frequency displacement and the change in reflectivity of the transparent microcapillary. The method comprises the stages of: the obtaining of a measurement of the reflectivity of the sample analytes within the capillary at each moment in time; the obtaining of a mechanical reference signal (T) of the change in resonance frequency of the microcapillary caused by the sample analytes over time; and the detection of the passage of the particle through an area of the capillary, and the obtaining of the points of passage of the ends of the analytes through the centre of the illuminated area, obtaining an optical signal ΔT.


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