The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2025

Filed:

Jun. 14, 2024
Applicants:

Yantai Patronus Biotech Co., Ltd., Yantai, CN;

Guangzhou Patronus Biotech Co., Ltd., Guangdong, CN;

Inventors:

Jing Jin, Guangzhou, CN;

Yu Zhou, Guangzhou, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); C07K 1/18 (2006.01); C07K 1/20 (2006.01);
U.S. Cl.
CPC ...
C12P 21/00 (2013.01); C07K 1/18 (2013.01); C07K 1/20 (2013.01);
Abstract

The present invention relates to a recombinant particle protein suitable for industrial production and a preparation method therefor. The product is prepared by the following method: transfecting a host cell with a plasmid vector comprising a sequence encoding the recombinant particle protein for expression in the cell, harvesting and disrupting the bacterial cells, heating, incubating with urea and sodium chloride, and performing chromatography. The particle size of the product is uniform, and the batch-to-batch consistency in particle size is good. The product prepared by the method can reduce the cost of large-scale industrial mass production, the method is simple to operate, and the product has low impurity residue and a good safety profile.


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