The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2025
Filed:
Oct. 07, 2021
Applicant:
Antheia, Inc., Menlo Park, CA (US);
Inventors:
Peter James Facchini, Calgary, CA;
Xue Chen, Calgary, CA;
Jeffrey C. Colbeck, Davis, CA (US);
Joseph E. Tucker, Strathmore, CA;
Assignee:
Antheia Inc., Menlo Park, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/70 (2006.01); C12N 9/88 (2006.01); C12P 17/18 (2006.01); C12N 15/70 (2006.01); C12P 13/22 (2006.01); C12P 17/12 (2006.01);
U.S. Cl.
CPC ...
C12P 17/182 (2013.01); C12N 9/88 (2013.01); C12N 15/70 (2013.01); C12P 13/22 (2013.01); C12P 17/12 (2013.01); C12Y 114/16002 (2013.01); C12Y 201/01128 (2013.01);
Abstract
Disclosed herein are methods that may be used for the synthesis of benzylisoquinoline alkaloids ('BIAs') such as alkaloid morphinan. The methods disclosed can be used to produce thebaine, oripavine, codeine, morphine, oxycodone, hydrocodone, oxymorphone, hydromorphone, naltrexone, naloxone, hydroxycodeinone, neopinone, and/or buprenorphine. Compositions and organisms useful for the synthesis of BIAs, including thebaine synthesis polypeptides, purine permeases, and polynucleotides encoding the same, are provided.