The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2025

Filed:

Aug. 24, 2019
Applicant:

Flagship Pioneering Innovations Vi, Llc, Cambridge, MA (US);

Inventors:

Maria Helena Christine Van Rooijen, Cambridge, MA (US);

Hok Hei Tam, Newton, MA (US);

Maier Steve Avendaño Amado, Cambridge, MA (US);

Barry Andrew Martin, Boston, MA (US);

Ignacio Martinez, Lexington, MA (US);

Piotr Stanislaw Kowalski, Cork, IE;

Nataliya Vladimirovna Nukolova, Cambridge, MA (US);

Yajie Niu, Lexington, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8213 (2013.01); C12N 15/827 (2013.01);
Abstract

Disclosed herein are plant-modifying compositions including a plurality of plant messenger packs (PMPs) (e.g., including a plant extracellular vesicle (EV), or segment, portion, or extract thereof), wherein the PMPs include a plant-modifying agent, and wherein the plant-modifying agent comprising the heterologous RNA. The compositions herein are useful in methods for modifying plants such as to increase plant fitness, wherein the increase in plant fitness comprising an increase in development, growth, yield, resistance to abiotic stressors, or resistance to biotic stressors.


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