The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2025
Filed:
Aug. 27, 2021
Applicant:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Inventors:
Nicholas A. Melosh, Menlo Park, CA (US);
Yuhong Cao, Palo Alto, CA (US);
Karl Martin Hjort, Lund, SE;
Amanda Jonsson, Stanford, CA (US);
Assignee:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12M 1/26 (2006.01); C12M 1/34 (2006.01); C12M 1/42 (2006.01); C12N 13/00 (2006.01); C12Q 1/24 (2006.01); B82Y 5/00 (2011.01); B82Y 15/00 (2011.01); B82Y 40/00 (2011.01);
U.S. Cl.
CPC ...
C12N 15/1003 (2013.01); C12M 33/04 (2013.01); C12M 35/02 (2013.01); C12M 41/38 (2013.01); C12N 13/00 (2013.01); C12Q 1/24 (2013.01); B82Y 5/00 (2013.01); B82Y 15/00 (2013.01); B82Y 40/00 (2013.01); C12Q 2523/307 (2013.01);
Abstract
Methods and apparatuses to non-destructively and periodically sample a small quantity of intracellular proteins and mRNA from the same single cell or cells for an extended period of time. Specifically, describe herein are non-perturbative methods for time-resolved, longitudinal extraction and quantitative measurement of intracellular proteins and nucleic acids from a variety of cell types using systems including nanostraws.