The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2025
Filed:
Jan. 30, 2024
Applicant:
The Board of Regents of the University of Oklahoma, Norman, OK (US);
Inventor:
Courtney W. Houchen, Edmond, OK (US);
Assignee:
The Board of Regents of the University of Oklahoma, Norman, OK (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 35/17 (2025.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C07K 16/40 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 35/17 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4251 (2025.01); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); A61K 2239/31 (2023.05); A61K 2239/38 (2023.05); C12Y 207/11001 (2013.01); G01N 33/5008 (2013.01); G01N 2800/52 (2013.01);
Abstract
CAR cells and humanized antibodies targeting DCLK1 expressed on/in tumor cells or circulating cancer cells are described as a new method of cancer treatment. The antibodies and cells are safe and effective in patients and can be used to treat cancer expressing the DCLK1 proteins.