The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2025

Filed:

Mar. 31, 2020
Applicant:

International Institute of Cancer Immunology, Inc., Suita, JP;

Inventors:

Haruo Sugiyama, Minoo, JP;

Shinji Sogo, Osaka, JP;

Masayoshi Sato, Osaka, JP;

Ryuki Kitamoto, Osaka, JP;

Yoshihiro Goto, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 40/11 (2025.01); A61K 40/42 (2025.01); C07K 7/08 (2006.01); C07K 14/82 (2006.01); C12N 5/0783 (2010.01); C12N 5/0784 (2010.01); C12N 5/0786 (2010.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 40/11 (2025.01); A61K 40/4243 (2025.01); C07K 14/82 (2013.01); C12N 5/0636 (2013.01); C12N 5/0638 (2013.01); C12N 5/0639 (2013.01); C12N 5/0645 (2013.01); A61K 2039/57 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/2307 (2013.01);
Abstract

The present invention relates to a method for activating helper T cells, which includes the step of activating helper T cells by adding a WT1 peptide to antigen presenting cells, wherein the WT1 peptide has the ability to bind to any MHC class II molecule of an HLA-DRB1*0101 molecule, an HLA-DRB1*0401 molecule, an HLA-DRB1*0403 molecule, an HLA-DRB1*0406 molecule, an HLA-DRB1*0803 molecule, an HLA-DRB1*0901 molecule, an HLA-DRB1*1101 molecule, an HLA-DRB3*0202 molecule, an HLA-DRB4*0101 molecule, an HLA-DPB1*0201 molecule or an HLA-DPB1*0301 molecule, and the like.


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