The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2025
Filed:
Nov. 06, 2024
Applicant:
Handa Oncology, Llc, San Jose, CA (US);
Inventors:
Fang-Yu Liu, San Jose, CA (US);
K.c. Sung, Tainan, TW;
Yu Zhang, Hangzhou, CN;
Shang Wei Qin, Hangzhou, CN;
John Duan, Tainan, TW;
George Kraft, San Jose, CA (US);
Assignee:
Handa Oncology, LLC, San Jose, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/22 (2006.01); A61K 9/48 (2006.01); A61K 31/47 (2006.01); A61P 1/12 (2006.01); A61P 1/14 (2006.01); C07C 305/06 (2006.01); C07C 317/04 (2006.01); C07D 215/20 (2006.01);
U.S. Cl.
CPC ...
C07D 215/22 (2013.01); A61K 9/4816 (2013.01); A61K 9/4825 (2013.01); A61K 9/4858 (2013.01); A61K 9/4866 (2013.01); A61K 31/47 (2013.01); C07C 317/04 (2013.01);
Abstract
The present invention relates to oral compositions comprising cabozantinib salts and at least one pharmaceutically acceptable excipient and methods of using the oral compositions to increase the oral bioavailability of the cabozantinib and reduce the adverse events associate with the oral administration of cabozantinib. The invention also relates to methods for preparing cabozantinib lauryl sulfate salts.