The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2025
Filed:
Apr. 16, 2021
Applicant:
Abclon Inc., Seoul, KR;
Inventors:
Assignee:
ABCLON INC., Seoul, KR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/32 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/33 (2025.01); A61K 40/42 (2025.01); A61K 47/54 (2017.01); A61K 47/68 (2017.01); C12N 5/0783 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6855 (2017.08); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/33 (2025.01); A61K 40/4205 (2025.01); A61K 47/545 (2017.08); A61K 47/6803 (2017.08); A61K 47/6851 (2017.08); C07K 16/32 (2013.01); C12N 5/0636 (2013.01); A61K 2039/505 (2013.01); A61K 2239/23 (2023.05); A61K 2239/31 (2023.05); A61K 2239/38 (2023.05); A61K 2239/59 (2023.05); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01);
Abstract
Disclosed herein are an anti-HER2 affibody and a switch molecule including a cotinine-conjugated anti-HER2 affibody. When applied in combination with Cot-sCART, the cotinine-conjugated anti-HER2 affibody reacts with HER2-positive cells to induce immune cell activity, thereby finding advantageous applications as switch molecules in sCART therapeutic agents.