The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2025

Filed:

Mar. 26, 2019
Applicants:

Changchun Bcht Biotechnology Co., Changchun, CN;

Jilin University, Changchun, CN;

Inventors:

Wei Kong, Changchun, CN;

Hui Wu, Changchun, CN;

Yao Sun, Changchun, CN;

Yongqing Guo, Changchun, CN;

Assignees:

CHANGCHUN BCHT BIOTECHNOLOGY CO., Changchun, CN;

JILIN UNIVERSITY, Changchun, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61K 39/00 (2006.01); A61P 25/28 (2006.01); A61P 37/04 (2006.01); C07K 14/47 (2006.01); C07K 16/44 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0007 (2013.01); A61P 25/28 (2018.01); A61P 37/04 (2018.01); A61K 2039/55561 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/6068 (2013.01); A61K 2039/6075 (2013.01); A61K 2039/6081 (2013.01); A61K 2039/627 (2013.01);
Abstract

The present invention discloses a phosphorylated polypeptide antigen vaccine, comprising at least two polypeptide fragments or conservatively modified variants thereof from human full-length Tau protein, wherein the polypeptide fragments or conservatively modified variants thereof contain phosphorylation sites. The present invention also discloses a complex vaccine formed by coupling a phosphorylated polypeptide antigen vaccine with a carrier. The polypeptide antigen vaccine and the complex vaccine can be used for preventing and/or treating tauopathy comprising Alzheimer's disease (AD).


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